Requests for Applications: Emotional Well-being and Economic Burden-Related Pilot Studies

(RFA-EMOT-ECON-50P-22-001)



Who we are: The Emotional Well-being and Economic Burden (EMOT-ECON) Research Network is a new initiative that will support EMOT-ECON research, i.e., research that seeks to develop innovative conceptual frameworks and theories to advance the science on emotional well-being and economic burden of disease and test the strategies needed to reduce the impact of this burden.


Economic burden of disease: There are numerous economic consequences of having a disease. These may include the money patients have to spend when getting medical care and managing their illness, and the time they may be out of work and the lost income, even if temporary. These may lead to medical financial hardship, distress, burden or toxicity.


Emotional well-being: Overall positive state of one’s emotions, life satisfaction, sense of meaning and purpose, and ability to pursue self-defined goals.


EMOT-ECON is funded by the National Center for Complementary and Integrative Health (NCCIH), the Office of Behavior and Social Sciences Research (OBSSR) and the Office of Disease Prevention (ODP) (U24AT011310). Principal Investigators are Maria Pisu, PhD, Professor, Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham and Michelle Martin, PhD, Professor, College of Medicine, University of Tennessee Health Science Center.


The EMOT-ECON network invites applications for pilot awards to provide project support for new or established investigators in the EMOT-ECON area of research. These pilot projects must involve primary data collection or secondary data analyses on EMOT-ECON research. Applications will be accepted in the following priority areas:

  • Ontology and measurement of emotional well-being (EWB) research to capture components of EWB in people with economic burden of disease. Examples of questions include, but are not limited to, identifying EWB components in people with economic burden of disease or financial hardship, or examining whether these components vary depending on when such burden or hardship occur across the lifespan.

  • Mechanistic research to identify mechanisms linking economic burden of disease to EWB. Examples of questions include, but are not limited to, examining whether emotion- or problem- focused coping in people with economic burden leads to lower stress which then leads to better EWB, or identifying mechanisms by which medical-related financial stress impacts EWB.

  • Prevention research to identify intervention strategies (e.g., stress-management, mind-body interventions, education, financial navigation interventions) that help individuals effectively cope with economic burden of disease and financial hardship and maintain or improve EWB. Examples of questions include but are not limited to, examining whether a stress management intervention (e.g., mindfulness meditation, yoga) in patients facing medical-related financial distress leads to better EWB, or whether providing information about costs of care or financial assistance leads to better EWB.

Applications that focus on economic burden or financial hardship broadly defined and not related to disease or focus on EWB only or economic burden of disease only, will be considered nonresponsive to this call.


RFA Guidelines and Terms of the Award

Funding Amount: $50,000 available* (2-3 grants may be funded)